Similarities in sequences or structures may either be the result of divergent or convergent trends. Homology is actually a measure of divergence between species, which shared a common origin. So a homology actually indicates the degree of divergent relationship. Homology study also helps us infer gene functionality. Within the homologous sequences proteins may either carry out the same functions or different functions. It is necessary to identify these differences between homologues. The proteins that carryout similar functions in different species are known as orthologues while the proteins that perform different (though related) functions are known as paralogues. Orthologous proteins hold the key in our study of molecular paleontology.
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Prokaryotes produce a similar effect by shifting reading frames during translation (Gene pp). The translation of rna into a protein also starts with a specific start and stop sequence (Gene pp). Once produced, the protein interacts with the many other proteins in the cell, according to the cell metabolism, finally producing the trait (Gene pp). The 3 types of rna: Messenger rna m-rna an rna copy of a gene; Ribosomal rna r-rna ribosomal structure; also includes the enzyme peptidyl transferase; Transfer rna t-rna transfer amino acids to ribosome; have anticodons which match the m-rna codons (Lecture pp). Mutations may occur in a several ways, for example natural variations within regulatory sequences appear to underlie many of the heritable characteristics seen in organisms and the influence of such variations on the trajectory of evolution through natural selection may be as large. Errors during dna replication may lead to the duplication of a gene, which may diverge over time and though the two sequences may remain the same or be only slightly seller altered, they are typically regarded as separate genes (Gene pp). Retrieved October 19, 2005 from: lecture 8: dna heredity Transcription translation ml, pages: 1 Term Paper Style: n/a Bibliography sources:. These specific genes which find expression in one species while remaining passive in another are responsible for the traits pertaining to the particular species. It would also give us an idea of the effect of the structural differences between the genes in the different species. Homology of sequences, homology is an important concept in studying genome sequences. Detection of homologous sequences is the essence of sequence analysis.
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